Introduction : Laparoscopic surgery, including laparoscopic cholecystectomy, gained worldwide attention quickly. One of the most significant advantages of laparoscopic cholecystectomy, over conventional cholecystectomy is less postoperative pain and shorter recovery period for patients to return to their normal lives. Despite this, patients do still have discomforts. Therefore, various methods have been tried for postoperative analgesia in laparoscopic cholecystectomies. \nBackground: It\'s been shown with studies that the application of analgesics before surgical trauma, could reduce post-traumatic spinal cord sensitivity and secondary hyperalgesia. If analgesic treatment initiated after the painful stimulus, because peripheral hypersensitivity and central nervous system hyperexcitability could already be developed, it would be difficult to manage the pain, postoperatively. It is believed that postoperative pain is a temporary neuropathic pain and gabapentin could be useful in reducing neuronal sensitization. \nAim: In our study, we aimed to assess the preemptive analgesic effect of gabapentin in laparoscopic cholecystectomy operations.\nMaterial - Method: 51 patients between ages 20 to 77 which are in ASA I-II groups planned for elective laparoscopic cholecystectomy, have been divided into two random groups as Group I (n=25) and Group II (n=26). To ensure preemptive effect, group I was introduced with P.O. 1200 mg gabapentin tablets, 2 hours before surgery. Group II however hasn\'t been treated as such. Both groups are treated with 1000 mg of I.V. paracetamol (10 mg/ml) 30 minutes before preoperative extubation as postoperative analgesic purposes. For postoperative analgesia, the first dose was initiated as 1000 mg intravenous paracetamol in 6 hour intervals, 6 hours after the initial application time. VAS scores and additional dose analgesic needs, the presence of nausea and/or vomiting were checked and recorded for the patients within the 2nd- 8th-14th and 20th hours after the operation. Patients with VAS scores 4 and/or higher, 1 mg/kg of pethidine was applied. For the patients with nausea and/or vomiting, 20 mg of intravenous slow infusion form of metoclopramide ampule was administered.\nResults: In the group treated with gabapentin, the postop VAS measurements taken in the 2nd, 8th and 14thhour, have been found to be significantly lower statistically, compared to the placebo given group. In the group that received gabapentin, the amount of additional dose of analgesic and antiemetic within the 24 hours after the operation, found to be significantly lower.\nDiscussion: In conclusion, it\'s been observed that the use of preemptive gabapentin in laparoscopic cholecystectomy has been effective in postoperative analgesia, and that it also reduced nausea and vomiting.