Abstract:Background. The emergence and spread of multidrug resistant/rifampicin resistant tuberculosis has posed an unprecedented global public health challenge. So far, there is scarcity of published work on the treatment outcome of the patients managed during the period WHO shorter injectable based regimen was used in Ebonyi State. Objective. To determining the treatment outcome of this short injectable regimen in Ebonyi State from October, 2017 to September, 2020 and identify the predictors of unsuccessful treatment outcome. Design. This was a total population study where all the 62 patients enrolled into the treatment during this period were recruited and a retrospective research design was utilized. Data were collected from the State DRTB registration log-book, patients’ folders and treatment cards using an adapted checklist. Information obtained were entered into the computer using SPSS version 25 Illinois USA. Simple frequencies, proportions, cross tabulation and logistic regression were used for data analysis and p value <0.05 was considered significant. Results. Twenty-five patients (40.3%), (14)22.6%, (5)8.1%. and (18)29% were cured, treatment completed, lost to follow up and died respectively. The predictors of unsuccessful treatment outcome were positive HIV status (P=0.042) and poor functional status (P=0.001). Discussion. There is need for the State TB program to channel more efforts toward sensitizing the public on the mode of spread of the disease, counselling of already identified cases, regular drugs supply, monitoring treatment progress to break the chains of transmission. Conclusion. The presence of HIV and poor functional status are major contributors to poor treatment outcomes.
Abstract:This article examines, for the first time, the relationship between learning style, motivation, and self-discipline, as factors that affect tertiary students� perceptions of online learning, from a retrospective perspective. The period between 2019 and 2022 was and remains one in which students are rethinking the components of teaching and learning. In addition, from the learners� perspective, social, cultural, and technological changes to which they were subject, including substantial changes to learning environments and learning methods, heightened learners� need to reconsider time planning. This study is based on 1,928 students enrolled in several academic institutions. We used a mixed-methods design for this exploratory research, incorporating qualitative and quantitative analysis, to develop the proposed Online Teaching Recommendations (SOTR) model. We used Structural Equation Modeling (SEM) for goodness-of-fit. Findings indicate that with respect to self-discipline, distractions and interruptions at home hinder students� online learning, but they do not lower students� assessments of the quality of online teaching. We may assume that students learn how to integrate online teaching in their everyday lives, and the short-term disadvantage may become a positive experience as students persist in their academic studies. Moreover, online teaching demands students� self-discipline, which also has no effect on perceived teaching quality. However, students� motivation declines following online teaching, s does self-discipline, which lowers perceived teaching quality. Students are concerned by the decline in social interactions with their class mates, caused by online learning, but this decline does not adversely affect their learning process. Findings of this study may contribute to improving teaching and learning for students who use digital tools for learning, especially in academic institutions where frontal instruction remains relevant and significant. Findings support the importance of the relationship between students� learning methods, motivation, and self-discipline, which are factors that affect students� perceptions of online learning. The question is whether academic instructors should enhance students� motivation to improve their self-discipline skills or whether these factors are related exclusively to students.
Abstract:We present a general conception of intrinsic metric and study some of its properties. We provide for general regular Dirichlet forms. Given a regular, strongly local Dirichlet form ℇ, the local doubling and local Poincaré inequalities are satisfied, we obtain that the intrinsic differential and distance structures of ℇ coincide.We obtain that an infinity harmonic function on R^n may be the minimizer for several different variational problem and we apply our results to Carnot-Caratheodory spaces. Giving the definitions and the main properties of Dirichlet spaces.
Abstract:Computer network specialists are in great request currently. The main objective of this research paper is learning the helpfulness of using Cisco Packet Tracer as a learning tool. This situation is measured significant to Higher Learning Organizations in instruction to confirm all clients with appropriate system helps. Consequently, computer network involves accepting of both theory and practical, later network simulation software should be suggested to overcome this problem.\n\nFrame relay is packet-switched equipment, which segments bandwidth between users on the switched network. Frame relay service providers accept that all users will not need the full volume of their bandwidth at all times. Therefore, in overall, frame relay is fewer costly than committed WAN lines, but clients are not certain bandwidth. All positions socket into the frame relay “cloud,” which is a collection of lots or hundreds of Frame relay switches and routers.\n\nFrame relay is a normal for packet switching WAN communications over great feature, numerical positions. Frame relay links run error detection but not error retrieval. It is active to close devices to demand a retransmission of missing packets. Frame relay networks simulate a \"continuously arranged\" association with PVCs (permanent virtual circuits). It is directing routers send data directly without forming a term. Frame Relay switches achieve error proving but not improvement.\n\nThe PPP over Frame Relay article permits a router to create end-to-end Point-to-Point Protocol (PPP) terms over Multi Point Frame relay. IP datagrams are elated over the PPP connection using RFC 1973 compliant Frame relay framing.
Abstract:In this paper, we introduce the involute curve concept according to\nthe modified orthogonal frame at non-zero points of curvature in the Minkowski 3-space. Besides, the modified frame for the involute curve is given. Further, the curvature and the torsion for the involute curve are introduced. Also, we give some necessary and sufficient conditions to the curve to be a general helix and a slant helix. Finally, some examples are introduced.
Abstract:The depletion of oxygen in a reactive stockpile that undergoes self-ignition process due to low-temperature oxidation reaction, is investigated in this paper. A reactive stockpile is the one whose materials contain carbon or hydrocarbon compounds that react readily with the oxygen trapped within the stockpile. The combustion process is modelled in a two-step reactive slab, that loses heat to the surrounding by convection. The process of combustion is so complicated and therefore, the mass transfer partial differential equation governing the problem cannot be solved exactly, but a numerical method is applicable. In this case, the equation was solved using Finite Difference Method (FDM), and Maple software was used to derive the solutions. The results plotted indicate that parameters like the oxygen Biot number help to retain the oxygen, whereas parameters such as the reaction rate enhance the depletion of oxygen.
Abstract:Rainfall trend and intensity are essential guides in understanding long-term changes in rainfall. This study aims to identify the trend and intensity of long-term rainfall at the main stations in the western region of Peninsular Malaysia between 1960 and 2010. Rainfall data were collected from 133 stations under the purview of the Department of Drainage and Irrigation of Malaysia. The analytical techniques used were descriptive analysis and the Mann-Kendall Trend Test. The results showed that from 1960 to 2010 the rainfall for all stations were in upward trend. However, Mann-Kendall Test (P = 1), showed that the trend was not significant. The average annual rainfall in the western region were classified as moderately wet having to decrease from a range of 1936 mm to 2635 mm, whereas, Dale’s average annual rainfall were in the range of 2540 mm to 2794 mm. The average rainfall variability for the western region during the study period was 699 mm, in contrary, Dale’s average rainfall variability from 1950 to 1959 was 254 mm. The maximum rainfall average for the western region (moderately wet) also lowered by 155 mm (6 per cent) from 1960 to 2010. The rainfall distribution showed that not all areas of the western province in Dale’s study received between 2540 mm and 2794 mm of rainfall annually. The implications of this study improve water management, especially in managing and planning the water supply more efficiently.
Abstract:Charcot arthropathy is characterized by progressive destruction of the joint that cause deformity and loss of function. Diagnosis of charcot arthropathy is challenging as it can mimic infection, rheumatoid or gouty arthritis. These conditions may co-exist or one condition followed another. We report a case of a young male who presented with charcot arthropathy of his right ankle. Hindfoot arthrodesis of the was done because of recurrent pain and instability that make walking difficult. During intraoperatively, we noted presence of tophaceous deposit on the tibiotalar surface.
Abstract:Background Delivery of optimal HD requires a well-functioning vascular access with a nominal blood flow rate of 400 mL/minute without access recirculation. Failure of access function limits the delivered dose of dialysis which in turn is one of the major determinants of survival on dialysis.9 Methods This is quazi experimental study, done in three hemodialysis centers of Khartoum State .Aimed to evaluate the effect of access care training program for nurses to prevent Hemodialysis access failure in Khartoum state. Total number of nurses from the three centers mentioned above was (54). At the start all participants were involved in pre assessment of knowledge and skills test. This was followed by an intense structured educational program in care of vascular access for hemodialysis, with special emphases on how to prevent access failure. The program included four lectures and one practical session for each group of nurses in the specified dialysis centers. The outcome of intervention was measured by assessing the access care in 40 dialysis patients regularly followed in these three centers. The data was collected using standardized, close-ended questionnaire through direct interview to the nurses. The performance of the nurses was observed using check list to assess the skills of nurses and check list to assess the vascular access of the patients. Data was analyzed using computer (SPSS program). Results The results show that, nurses who participated in the study have highly significant scores of knowledge (80.86%) at post-intervention than the score at pre intervention (46.13%). Also regarding skills they have highly significant scores of skills (71.4%) at post intervention than the score at pre-intervention (12.6%).when access condition was examined gave low present of failure (32.5%) at post intervention than the score at previous study (92.85%). Conclusions In this study access care training programme for nurses changed significantly their knowledge and skills. Thus failure rate was reduced as outcome of this training programme. Recommendation The study recommended that Developing of modules for standardized training programme for hemodialysis nurses and encourage fund raising projects by staff members for purpose of developing evidence base practice researches.
Abstract:COVID-19 is an infectious disease caused by the new coronavirus, SARS-CoV2, with a heterogeneous clinical course, ranging from asymptomatic patients to critically ill patients with multiple organ dysfunction. It is well known that the severity of the disease is secondary to a dysregulated inflammatory response known as a cytokine storm. Hemoabsorptive therapies, such as the Cytosorb device, could be a useful treatment alternative in severely ill patients with cytokine storm, due to its beneficial effect by purifying inflammatory mediators in septic patients, postoperative of cardiovascular surgery, with pancreatitis, and even poisoned.